The University of Florida has utilized its own wastewater treatment plant since 1948. The original plant was located at the corner of Museum Road and North-South Drive on the U.F. campus. In 1991, construction of a new facility was begun. The new Water Reclamation Facility was completed in 1994, and is located on North-South Drive, just south of the original site. The new facility is a prototype plant, using the BioDenipho process to treat wastewater.

The University of Florida Water Reclamation Facility is a biological nitrogen and phosphorus removal, or BioDenipho plant. It has two anaerobic tanks, two oxidation ditches, series flow patterns and alternating ambient conditions within the oxidation ditches. A BioDenipho plant resembles a Bardenpho plant where anoxic and aerobic processes take place separately with a clarifier and a return sludge pump system. A wastewater treatment plant employing the BioDenipho process also resembles a conventional oxidation ditch treatment plant where aeration or oxygenation of mixed liquor takes place, a clarifier is used for settling the mixed liquor, and a return sludge pumping system is utilized.

The major components common to both conventional oxidation ditch and BioDenipho processes are a closed-loop reactor basin where aeration of mixed liquor takes place, a clarifier for settling the mixed liquor, and a return sludge pumping system. The feature distinguishing the BioDenipho plant is that the anaerobic tank is located prior to the oxidation ditches.